Osteoactivin/GPNMB Antibody

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Target Osteoactivin/GPNMB
Applications Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA Capture
Unit 100 ug
Format Immunogen affinity purified
Concentration LYOPH
NCBI Gene Aliases HGFIN, NMB
Description Osteoactivin/GPNMB Antibody
Conjugate/Tag/Label Unconjugated
Reactivity Human
Isotype IgG
Host Goat
References Hong SB, Oh H, Valera VA, Baba M, Schmidt LS, Linehan WM. Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization. PLoS One. 2010 Dec 29;5(12):e15793.

Patel-Chamberlin M, Wang Y, Satirapoj B, Phillips LM, Nast CC, Dai T, Watkins RA, Wu X, Natarajan R, Leng A, et al. Hematopoietic growth factor inducible neurokinin-1 (Gpnmb/Osteoactivin) is a biomarker of progressive renal injury across species. Kidney Int. 2011 May;79(10):1138-48.

Rose AA, Grosset AA, Dong Z, Russo C, Macdonald PA, Bertos NR, St-Pierre Y, Simantov R, Hallett M, Park M, et al. Glycoprotein nonmetastatic B is an independent prognostic indicator of recurrence and a novel therapeutic target in breast cancer. Clin Cancer Res. 2010 Apr 1;16(7):2147-56.
Primary / Secondary Primary
Keywords 21209915, 20215530, 21389974
Entrez GeneID 10457
Immunogen Mouse myeloma cell line NS0-derived recombinant human Osteoactivin isoform b, corresponding to Lys23-Asn486
Validated Applications WB, ELISA, IHC, IHC-p
NCBI Full Gene Name glycoprotein (transmembrane) nmb
Validated Species Reactivity Human (Hu)
Scrazzl Core Name Osteoactivin/GPNMB Antibody
NCBI Target Species man