Rabbit Anti-RGS2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-RGS2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 48-550

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Target RGS2
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Target/Molecule Synonym RGS2, G0S8, regulator of g-protein signaling 2, rgs2
Unit 0.05 mg
Format Purification: Protein G ColumnFormulation: Weight: 50 µg Volume: 100 µl Concentration: 0.5 mg/ml
Description Regulators of G-protein signaling (RGSs) are a protein family containing a conserved 120 amino acid domain (RGS domain), which bind directly to activated G-alpha subunits (Gai and Gaq) and act as GTPase-activating proteins (GAPs). One of these proteins, RGS2, is expressed in thyroid, heart. thyroid, and monocyte-derived DCs. The function of RGS2 as a regulator of Gq is also dependent on regulatory sequences in its amino-terminal domain that direct its localization to the plasma membrane. Recent studies have shown that RGS2 is critical for blood pressure homeostasis, and has been suggested to serve as an effector of the NO-cGMP pathway that promotes vascular relaxation based on studies of aortic rings in vitro.RGS2 antibody was raised against a synthetic peptide within amino acid residues 1-50 of RGS2. (Human)RGS2 antibody is supplied in PBS, 0.2% gelatin, 0.05% sodium azide.RGS2 antibody can be used for detection of RGS2 by WB (1 - 3 µg/ml), IHC-parafin (20 µg/ml).RGS2 antibody can be stored at -70ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 48-550 RRID:AB_1948453
Company ProSci, Inc
Clonality Polyclonal
Isotype IgG