RGS21 Antibody

  • RGS21 Antibody

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    CatalogueID : 5209

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Target RGS21
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym RGS21 Antibody: Regulator of G-protein signaling 21
Format RGS21 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
Description RGS21 Antibody: Regulator of G-protein signaling (RGS) proteins contain an 120 amino acid conserved domain, termed the RGS domain, that acts as a GTPase-activating protein that acts to reduce the signal transmitted by the receptor-activated G-alpha subunit. RGS21 is a recently identified member of this family that has been reported to be selectively expressed in subpopulations of taste bud cells and co-expressed with bitter and sweet transduction components such as alpha-gusticin, phospholipase Cbeta2, T1R2/T1R3 sweet taste receptors and T2R bitter taste receptors. Other reports indicate that RGS21 is more widely expressed. Binding assays demonstrate that RGS21 binds alpha-gusticin in a conformation-dependent manner and may do the same with T1R receptors, suggesting that RGS21 may play a role in sweet and bitter taste transduction processes
Cite This Product ProSci cat# 5209 RRID:AB_10906764
Company ProSci
Type Antibody
Accession Number NP_001034241
Immunogen RGS21 antibody was raised against a 16 amino acid synthetic peptide near the center of human RGS21
Isotype IgG
Molecule Name RGS21 regulator of G-protein signaling 21
Clonality Polyclonal