Rabbit Anti-RGS4 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-RGS4 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 30-039

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Target RGS4
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB
Target/Molecule Synonym RGS4, regulator of G-protein signalling 4
Unit 0.05 mg
Format Purification: Rabbit IgG is purified by peptide affinity chromatography method.
Description Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein negatively regulates signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 4 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. Regulator of G protein signaling 4 protein is 37% identical to RGS1 and 97% identical to rat Rgs4. This protein negatively regulate signaling upstream or at the level of the heterotrimeric G protein and is localized in the cytoplasm.NP_00560423kDa, 34kDaPolyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human RGS4.Cat. No. 1205 - Jurkat Cell LysateAntibody is supplied in PBS buffer with 2% sucrose. Product may ship lyophilized. To reconstitute add 100µl of distilled water making the final concentration 1 mg/ml.RGS4 antibody can be used for Western blot at a suggested dilution at 1.0µg/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50, 000 - 100, 000 as secondary antibody.Antibody is lyophilized from PBS buffer with 2% sucrose. Add 50 µl of distilled water. Final antibody concentration is 1 mg/ml. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
Cite This Product ProSci cat# 30-039 RRID:AB_1948456
Company ProSci, Inc
Clonality Polyclonal
Uniprot ID Q0R4E4