RHAMM Antibody

  • RHAMM Antibody

    from ProSci
    CatalogueID : 6189

  • Contact Vendor

Target Hmmr
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym RHAMM Antibody: Hyaluronan mediated motility receptor, HMMR, CD168, IHABP
Format RHAMM Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases CD168, MGC119495, MGC119494, IHABP, RHAMM
Description RHAMM Antibody: The hyaluronan-mediated motility receptor, also known as RHAMM, was initially identified as a soluble protein that could be released by sub-confluent migrating cells, promoting cell motility and invasion via interactions with hyaluronan (HA) and the cell surface. While RHAMM is normally poorly expressed in most normal tissues and is not required for embryonic development or normal cell homeostasis functions, its expression is increased during wound repair in response to hypoxia and fibrogenic factors. However, its overexpression is transforming in multiple types of cancers and is required for maintaining RAS transformation. RHAMM associates with BRCA1 and BARD1, attenuating the mitotic-spindle-promoting activity of RHAMM, which may contribute to tumor progression by promoting genomic instability
Cite This Product ProSci cat# 6189 RRID:AB_10905312
Company ProSci
Type Antibody
Accession Number NP_036617
Immunogen RHAMM antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RHAMM
Isotype IgG
Molecule Name HMMR yaluronan-mediated motility receptor
Clonality Polyclonal