RHOC Antibody

  • RHOC Antibody

    from ProSci
    CatalogueID : 27-070

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Target RHOC
Species Cross Reactivity Homo sapiens, Mus musculus, Oryctolagus cuniculus, Canis lupus familiaris
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Polyclonal
Unit 0.05 mg
Format Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/ml. Powder
Concentration Lyophilized
Description RHOC Is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. RHOC is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of RHOC is associated with tumor cell proliferation and metastasis.This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified. RHOC (ras homolog gene family, member C)
Cite This Product ProSci cat# 27-070 RRID:AB_10909202
Company ProSci, Inc
Accession Number NP_786886
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RHOC.
Molecular Weight 22 kDa