FGD1 Antibody

  • FGD1 Antibody

    from ProSci
    CatalogueID : 27-391

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Target fgd1
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Polyclonal
Unit 0.05 mg
Format Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/ml. Powder
Concentration Lyophilized
Description FGD1 contains Dbl (DH) and pleckstrin (PH) homology domains. It can bind specifically to the Rho family GTPase Cdc42Hs and stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. FGD1 has an essential role in embryonic development, and FGD1 gene mutations result in the human developmental disorder, Aarskog-Scott syndrome. FGD1 (FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia))
Cite This Product ProSci cat# 27-391 RRID:AB_10907461
Company ProSci, Inc
Accession Number NP_004454
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human FGD1.
Molecular Weight 107 kDa