Rkhd1 Antibody

  • Rkhd1 Antibody

    from ProSci
    CatalogueID : 4835

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Target Mex3d
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym Rkhd1 Antibody: RING finger and KH domain-containing protein 1, MEX3D, TINO, RING finger protein 193, RNF193
Format Rkhd1 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases MEX-3D, OK/SW-cl.4, MEX3, RNF193, KIAA2031, TINO, RKHD1
Description Rkhd1 Antibody: Rkhd1, also known as TINO or MEX3D is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd1, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd1 binds to the AU-rich element in the 3'-untranslated region of Bcl-2 mRNA and is thought to be a negative regulator of Bcl-2 expression. Rkhd3 and Rkhd4, but not Rkhd1, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover
Cite This Product ProSci cat# 4835 RRID:AB_10907656
Company ProSci
Type Antibody
Accession Number Q86XN8
Immunogen Rkhd1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human Rkhd1
Isotype IgG
Molecule Name MEX3D mex-3 homolog D (C. elegans)
Clonality Polyclonal