Rkhd2 Antibody

  • Rkhd2 Antibody

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    CatalogueID : 4857

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Target MEX3C
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Target Species Homo sapiens
Target/Molecule Synonym Rkhd2 Antibody: RING finger and KH domain-containing protein 2, RING finger protein 194, MEX3C, RNF194
Format Rkhd2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases RNF194, FLJ38871, RKHD2, MEX-3C
Description Rkhd2 Antibody: Rkhd2, also known as MEX3C is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd2, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. It has been suggested that genetic variations in Rkhd2 may be associated with susceptibility to essential hypertension type 8. Rkhd3 and Rkhd4, but not Rkhd2, co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover
Cite This Product ProSci cat# 4857 RRID:AB_10912638
Company ProSci
Type Antibody
Accession Number NP_057710
Immunogen Rkhd2 antibody was raised against a 15 amino acid synthetic peptide from near the carboxy terminus of human RKHD2
Isotype IgG
Molecule Name MEX3C mex-3 homolog C (C. elegans)
Clonality Polyclonal