RKHD3 Antibody

  • RKHD3 Antibody

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    CatalogueID : 6641

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Target mex3b
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym RKHD3 Antibody: RING finger and KH domain-containing protein 3, MEX3B, Ring finger protein 195, RNF195
Format RKHD3 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases DKFZp434J0617, MEX-3B, RNF195, MGC117199, RKHD3
Description RKHD3 Antibody: Rkhd3, also known as MEX3B is a member of a novel family of four homologous human MEX3 proteins each containing two heterogeneous nuclear ribonucleoprotein K homology (KH) domains and one carboxy-terminal RING finger module. MEX3 proteins, including Rkhd3, are phosphoproteins that bind RNA through their KH domains and shuttle between the nucleus and the cytoplasm via the CRM1 export pathway. These proteins are a novel family of evolutionarily conserved RNA-binding proteins, differentially recruited to P bodies and potentially involved in post-transcriptional regulatory mechanisms. Rkhd3 is thought to act as a mechanism to fine-tune mRNA regulation in early Xenopus development, and with Rkhd4, but not Rkhd1, will co-localize with both the hDcp1a decapping factor and Argonaute (Ago) proteins in processing bodies (P bodies), recently characterized as centers of mRNA turnover
Cite This Product ProSci cat# 6641 RRID:AB_10942144
Company ProSci
Type Antibody
Accession Number NP_780575
Immunogen RKHD3 antibody was raised against a 16 amino acid synthetic peptide from near the center of human RKHD3
Isotype IgG
Molecule Name MEX3B mex-3 homolog B
Clonality Polyclonal