RMI1 Antibody

  • RMI1 Antibody

    from ProSci
    CatalogueID : 26-127

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Target rmi1
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Polyclonal
Unit 0.05 mg
Format Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/ml. Powder
Concentration Lyophilized
Description RMI1 is an essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. RMI1 promotes TOP3A binding to double Holliday junctions (DHJ) and hence stimulates TOP3A-mediated dissolution. RMI1 is required for BLM phosphorylation during mitosis. Within the BLM complex, RMI1 is required for BLM and TOP3A stability.RMI1 is a component of protein complexes that limit DNA crossover formation via the dissolution of double Holliday junctions (Raynard et al., 2006 [PubMed 16595695]). RMI1 (RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae))
Cite This Product ProSci cat# 26-127 RRID:AB_10911933
Company ProSci, Inc
Accession Number NP_079221
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human RMI1.
Molecular Weight 70 kDa