SAP18 Antibody

  • SAP18 Antibody

    from ProSci
    CatalogueID : 28-920

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Target SAP18
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Polyclonal
Unit 0.05 mg
Format Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/ml. Powder
Concentration Lyophilized
Description Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. SAP18 is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter.Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. SAP18 (Sin3A-associated protein, 18kDa)
Cite This Product ProSci cat# 28-920 RRID:AB_10906472
Company ProSci, Inc
Accession Number NP_005861
Immunogen Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SAP18.
Molecular Weight 18 kDa