Mouse Anti-Human STAT1 Monoclonal Antibody, Unconjugated, Clone SAT-84

  • Mouse Anti-Human STAT1 Monoclonal Antibody, Unconjugated, Clone SAT-84

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    CatalogueID : 48-802

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Target STAT1
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Clone Clone SAT-84
Target Species Homo sapiens
Target/Molecule Synonym STAT1, DKFZP686B04100, ISGF-3, STAT91, signal transducer and activator of transcription 1-alpha/beta, stat1
Unit 0.05 mg
Format Purification: Protein G ColumnFormulation: Weight: 50 µg Concentration: 0.5 mg/ml
Description STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-a, IFN-b, IFN-g and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1). STAT1 has two forms, the 91 kDa STAT1a and the 84 kDa STAT1b which are encoded by the same gene with splicing variant.STAT1 monoclonal antibody was raised against a peptide of STAT1. (Human)STAT1 monoclonal antibody is supplied in phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.STAT1 antibody can be used for detection of STAT1 by WB, IHC-parafin (15 µg/ml).STAT1 monoclonal antibody can be stored at 4ºC, avoid freezing.
Cite This Product ProSci cat# 48-802 RRID:AB_1948840
Company ProSci, Inc
Clonality Monoclonal
Isotype IgG1
Uniprot ID P42225