SATB2 Antibody

  • SATB2 Antibody

    from ProSci
    CatalogueID : 4627

  • Contact Vendor

Target frr
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym SATB2 Antibody: DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2
Format SATB2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases KIAA1034, FLJ32076, MGC119477, MGC119474, FLJ21474
Description SATB2 Antibody: Human special AT-rich sequence-binding protein-2 (SATB2) is a nuclear matrix/scaffold-associated region DNA-binding protein. Like its homolog SATB1, SATB2 selectively binds double-stranded, special AT-rich DNA sequences, but is expressed primarily in a subset of postmitotic, differentiating neurons in the neocortex. Mice deficient in SATB exhibit craniofacial abnormalities and defects in osteoblast differentiation and function. SATB2 also interacts with and enhances the activity of Runx2 and ATF4, two transcription factors that regulate osteoblast differentiation, indicating that SATB2 acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation. Recent experiments have shown that SATB2 interacts with histone deacetylase 1 and metastasis-associated protein 2, two proteins that are involved in chromatin remodeling, suggesting that SATB2 may also be involved in mediating epigenetic influences during cortical development
Cite This Product ProSci cat# 4627 RRID:AB_10909690
Company ProSci
Type Antibody
Accession Number Q9UPW6
Immunogen SATB2 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human SATB2
Isotype IgG
Molecule Name SATB2 SATB homeobox 2
Clonality Polyclonal