Rabbit Anti-Human ACE2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human ACE2 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3217

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Target ACE2
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym ACE2 Antibody:
Format ACE2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases ACEH, DKFZp434A014
Description ACE2 Antibody: Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function
Cite This Product ProSci cat# 3217 RRID:AB_712925
Company ProSci
Type Antibody
Accession Number NP_068576
Immunogen ACE2 antibody was raised against a synthetic peptide corresponding to amino acids near the C-terminus of human ACE2
Isotype IgG
Molecule Name ACE2 angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
Clonality Polyclonal