Rabbit Anti-Acinus (CT) Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Acinus (CT) Polyclonal Antibody, Unconjugated

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    CatalogueID : 2217

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Target ACIN1
Species Cross Reactivity Plant (Species unspecified), Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym Acinus Antibody:
Format Acinus Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases fSAP152, ACINUS, ACN, KIAA0670, DKFZp667N107
Description Acinus Antibody: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis. CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE. A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus). Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei. Acinus also induces apoptotic chromatin condensation in cells. Acinus is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'
Cite This Product ProSci cat# 2217 RRID:AB_203121
Company ProSci
Type Antibody
Accession Number AAD56724
Immunogen Acinus antibody was raised against a peptide corresponding to amino acids near the carbosy terminus of human AcinusL, which are identical to those of mouse Acinus
Isotype IgG
Molecular Weight 220 kDa
Molecule Name ACIN1 apoptotic chromatin condensation inducer 1
Clonality Polyclonal