Mouse Anti-Human Akt2 Monoclonal Antibody, Unconjugated, Clone 1G8C12

  • Mouse Anti-Human Akt2 Monoclonal Antibody, Unconjugated, Clone 1G8C12

    from ProSci
    CatalogueID : 32-105

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Target AKT2
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Clone 1G8C12
Target Species Homo sapiens
Target/Molecule Synonym PKBB, PRKBB, PKBBETA, RAC-BETA
Unit 0.1 ml
Format Formulation: Ascitic fluid containing 0.03% sodium azide. Purified antibody available at no extra cost.
Description Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2 ), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3.They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance.Further, Akt2 plays a specific role in muscle differentiation.GI Number: 208Immunogen: Ni-NTA purified truncated recombinant Akt2 expressed in E. Coli strain BL21 (DE3).Application: Western Blot:1:100 - 1:500 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.Positive Control 1: Cat. No. 1202 - A431 Cell LysateStorage: Akt2 monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-105 RRID:AB_1945031
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG2b
Uniprot ID Q60823