Mouse Anti-AKT3 Monoclonal Antibody, Unconjugated, Clone 66C12471

  • Mouse Anti-AKT3 Monoclonal Antibody, Unconjugated, Clone 66C12471

    from ProSci
    CatalogueID : 48-641

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Target AKT3
Species Cross Reactivity Mus musculus, Rattus norvegicus
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Clone Clone 66C12471
Target/Molecule Synonym AKT3, DKFZP434N0250, EC, PKBG, PRKBG, RAC-GAMMA, RAC-PK-GAMMA, STK-2, akt3, AKT3/PKBgamma, PKB gamma, pkbg, prkbg, protein kinase B gamma, rac-gamma, RAC-PK-gamma, serine/threonine kinase rac-gamma, v-akt murine thymoma viral oncogene homolog 3
Unit 0.05 mg
Format Purification: Protein G ColumnFormulation: Weight: 50 µg Concentration: 0.5 mg/ml
Description Akt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.Immunogen: AKT3 monoclonal antibody was raised against a synthetic peptide corresponding to amino acid residues 119-136 of AKT3. (Human)Application: AKT3 antibody can be used for detection of AKT3 by WB (1 - 2 µg/ml), IHC-parafin (10 µg/ml).Buffer: AKT3 monoclonal antibody is supplied in PBS, 0.05% BSA, 0.05% sodium azide.Storage: AKT3 monoclonal antibody can be stored at 4ºC or -20ºC, Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 48-641 RRID:AB_1945037
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID Q9WUA6