Mouse Anti-Human APP Monoclonal Antibody, Unconjugated, Clone 1B11F3

  • Mouse Anti-Human APP Monoclonal Antibody, Unconjugated, Clone 1B11F3

    from ProSci
    CatalogueID : 32-113

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Target APP
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Clone Clone 1B11F3
Target Species Homo sapiens
Target/Molecule Synonym APP
Unit 0.1 ml
Format Formulation: Ascitic fluid containing 0.03% sodium azide. Purified antibody available at no extra cost.
Description Amyloid precursor protein(APP),with 32-amino acid protein (about 35 kDa), is part of a super-family of transmembrane and secreted proteins. It appears to have a number of roles, including regulation of haemostasis and mediation of neuroprotection. APP undergoes alternative splicing, resulting in several isoforms . Proteolytic cleavage of amyloid precursor protein leads to the formation of the 4 kDa amyloid beta/A4 protein, which is present in human platelets. APP is also involved in the formation of neurofibrillary tangles and plaques that characterize the senile plaques of Alzheimer patients.GI Number: 351Immunogen: Ni-NTA purified truncated recombinant APP expressed in E. Coli strain BL21 (DE3).Application: Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.Storage: APP monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-113 RRID:AB_1945154
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG2a
Uniprot ID P12023