Rabbit Anti-APP (AbNT) Polyclonal Antibody, Unconjugated

  • Rabbit Anti-APP (AbNT) Polyclonal Antibody, Unconjugated

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    CatalogueID : 2133

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Target APP
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Homo sapiens
Target/Molecule Synonym APP Antibody: APP AbNT, APP AbNT
Format APP Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases CTFgamma, CVAP, AAA, ABETA, AD1, PN2, ABPP, APPI
Description APP Antibody: Accumulation of the amyloid-beta peptide (Abeta) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The beta-amyloid protein precursor (APP) is cleaved by beta-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for gamma-secretase to generate the 4 kDa amyloid-beta peptide (Abeta), which is deposited in the brains of all suffers of Alzheimer's disease
Cite This Product ProSci cat# 2133 RRID:AB_203130
Company ProSci
Type Antibody
Accession Number CAA30050
Immunogen APP antibody was raised against a peptide corresponding to amino acids of human amyloid A4 protein precursor (APP) corresponding to the amino terminus of the 4K Ab peptide generated by b- and g-secretases The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig, and chicken
Isotype IgG
Molecule Name APP amyloid beta (A4) precursor protein
Clonality Polyclonal