Rabbit Anti-Human APC2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human APC2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-382

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Target APC2
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IP
Target Species Homo sapiens
Target/Molecule Synonym APC2, ANAPC2, APCL, KIAA1406, apcl protein
Unit 0.05 mg
Format Purification: Sterile FiltrationFormulation: Volume: 50 µl Concentration: 85 mg/ml
Description APC2, also known as Anaphase promoting complex subunit 2, APC2, Cyclosome subunit 2, and ANAPC2, is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/cyclosome protein complex promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitors, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains at least eleven subunits. The composition of APC is highly conserved in organisms from yeast to humans. APC2 is a cullin family member that interacts through the cullin domain with ANAPC11 and UBCH10.Immunogen: APC2 antibody was raised against amino acids 810-822 of APC2. (Human)Application: APC2 antibody can be used for detection of APC2 by WB (1:500 - 1:1000), IP, ELISA (1:2000 - 1:10000), IHC-parafin (1:500).Buffer: APC2 antibody is supplied in 0.01% sodium azide.Storage: APC2 antibody can be stored at 4ºC or -20ºC. Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 49-382 RRID:AB_1945116
Company ProSci, Inc
Type Polyclonal Antibody