Rabbit Anti-Human Clusterin Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human Clusterin Polyclonal Antibody, Unconjugated

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    CatalogueID : 3856

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Target CLU
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Homo sapiens
Target/Molecule Synonym Clusterin Antibody: Clusterin, Complement lysis inhibitor, CLI, Apolipoprotein J, ApoJ
Format Clusterin Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases CLI, SGP2, APOJ, MGC24903, SGP-2, KUB1, SP-40, TRPM-2, TRPM2
Description Clusterin Antibody: Clusterin, also known as Apolipoprotein J (ApoJ), is a ubiquitous multifunctional glycoprotein that can interact with a broad spectrum of molecules such as complement components, various receptors, and the Alzheimer's b-amyloid peptide. Clusterin expression is increased in Alzheimer's disease brain tissue and clusterin-immunoreactive amyloid plaques are found associated with phospho-tau-positive dystrophic neurites and it has been suggested that clusterin facilitates the conversion of diffuse b-amyloid deposits into amyloid and enhances tau phosphorylation in neurites around these plaques. Other reports show that clusterin expression is decreased in proliferating cells and is upregulated in quiescent and senescent cells, suggesting that it may also play a role in aging and tumorigenesis suppression. Clusterin exists in at least two distinct isoforms
Cite This Product ProSci cat# 3856 RRID:AB_712979
Company ProSci
Type Antibody
Accession Number NP_001822
Immunogen Clusterin antibody was raised recombinant human Clusterin isoform 1
Isotype IgG
Molecule Name CLU clusterin
Clonality Polyclonal