Rabbit Anti-ARFGAP1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-ARFGAP1 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-507

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Target ARFGAP1
Species Cross Reactivity Mus musculus, Rattus norvegicus, Bos taurus, Gallus gallus, Canis lupus familiaris, Pan troglodytes
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target/Molecule Synonym ARFGAP1, ARF1GAP, BA261N11.3, FLJ10767, HRIHFB2281, MGC39924
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg Volume: 50 µl Concentration: 1 mg/ml
Description ASAP1 (also known as AMAP1, 130-kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein, PIP2-dependent ARF1 GAP,ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, Differentiation-enhancing factor 1, DEF-1) is an Arf-directed GTPase activating protein that is a substrate for the kinases Src and FAK and has been implicated in the regulation of membrane traffic, focal adhesions and invadopodia/podosomes. Phosphorylation of ASAP1 at tyrosine 782 has been found to affect enzymatic and some biological activities, including the function of invadopodia. ASAP1 is expressed in many tissues but is most abundant in the testis, brain, lung and spleen. A heightened expression was seen in the adipose tissue from obese (ob) and diabetic (db) animals. Multiple transcript variants have been reported for this proteinSpecificity: pTyr782Immunogen: ARFGAP1 antibody was raised against amino acids 777-787 of ARFGAP1. (Mouse)Application: ARFGAP1 antibody can be used for detection of ARFGAP1 by WB (1:500 - 1:2000), ELISA (1:4000 - 1:16000), IF, IHC-parafin (20 - 40 µg/ml).Buffer: ARFGAP1 antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.Storage: ARFGAP1 antibody can be stored at 4ºC or -20ºC. Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 49-507 RRID:AB_1945168
Company ProSci, Inc
Type Polyclonal Antibody