Rabbit Anti-Bak Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Bak Polyclonal Antibody, Unconjugated

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    CatalogueID : 3347

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Target BAK1
Species Cross Reactivity Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB
Target Species Homo sapiens
Target/Molecule Synonym Bak Antibody:
Format Bak Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases BCL2L7, MGC117255, CDN1, BAK-LIKE, BAK, MGC3887
Description Bak Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bak, a pro-apoptotic Bcl-2 family member, is an oligomeric protein that localizes to the mitochondria. It is thought to share significant functional homology with Bax, another pro-apoptotic Bcl-2 family member, as disruption of bak or bax has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking bak and bax show decreased apoptotic capability
Cite This Product ProSci cat# 3347 RRID:AB_735309
Company ProSci
Type Antibody
Accession Number Q16611
Immunogen Bak antibody was raised against a peptide corresponding to 13 amino acids near the amino-terminus of human Bak
Isotype IgG
Molecule Name BAK1 BCL2-antagonist/killer 1
Clonality Polyclonal