Rabbit Anti-Bid Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Bid Polyclonal Antibody, Unconjugated

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    CatalogueID : 3353

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Target BID
Species Cross Reactivity Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym Bid Antibody:
Format Bid Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases MGC42355, MGC15319, FP497
Description Bid Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bid, a pro-apoptotic Bcl-2 family member, is cleaved by caspase-8 in response to apoptotic signals, exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein. The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize
Cite This Product ProSci cat# 3353 RRID:AB_735314
Company ProSci
Type Antibody
Accession Number AAH36364
Immunogen Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid
Isotype IgG
Molecule Name BID BH3 interacting domain death agonist
Clonality Polyclonal