Rabbit Anti-CTRP2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-CTRP2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 3561

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Target C1qtnf2
Species Cross Reactivity Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym CTRP2 Antibody:
Format CTRP2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases CTRP2, zacrp2
Description CTRP2 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation
Cite This Product ProSci cat# 3561 RRID:AB_735320
Company ProSci
Type Antibody
Accession Number NP_114114
Immunogen CTRP2 antibody was raised against a 16 amino acid synthetic peptide from near the amino-terminus of human CTRP2
Isotype IgG
Molecule Name C1QTNF2 C1q and tumor necrosis factor related protein 2
Clonality Polyclonal