Mouse Anti-Human C4BPA Monoclonal Antibody, Unconjugated, Clone 40093

  • Mouse Anti-Human C4BPA Monoclonal Antibody, Unconjugated, Clone 40093

    from ProSci
    CatalogueID : 49-802

  • Contact Vendor

Target C4bpa
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA
Clone Clone 40093
Target Species Homo sapiens
Target/Molecule Synonym C4BPA, C4BP, PRP, c4b-binding protein alpha chain
Unit 0.05 mg
Format Purification: Protein A ColumnFormulation: Weight: 50 µg
Description Recognises complement component 4 binding protein (C4bp). There are three variants of C4bp, composed of alpha and beta chains. The predominant form is a 570 kDa complex of 7 alpha chains and 1 beta chain. The other complexes formed are a 530 kDa homoheptamer of alpha chains or a 500 kDa complex of 6 alpha chains and 1 beta chain. C4bp regulates the activation of the classical complement pathway. It is a cofactor to the C3b/C4b inactivator, crucial to the proteolytic cleavage of C4b and important in cleavage of C3b. C4bp also regulates the C4bC2a complex (C3 convertase), accelerating its degradation by dissociating the complement fragment C2a. Both the C4bp alpha and beta chains interact with anticoagulant protein S and C4bp alpha binds protein S. C4bp is expressed in the blood serum.Immunogen: C4BPA monoclonal antibody was raised against native C4BPA. (Human)Application: C4BPA monoclonal antibody can be used for detection of C4BPA by ELISA.Buffer: C4BPA monoclonal antibody is supplied in BBS, pH 8.4, 0.02% sodium azide.Storage: C4BPA monoclonal antibody can be stored at 4ºC or -20ºC. Avoid repeated freezing and thawing. Store undiluted.
Cite This Product ProSci cat# 49-802 RRID:AB_1945415
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG2b
Uniprot ID P08607