Rabbit Anti-Human NOD2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human NOD2 Polyclonal Antibody, Unconjugated

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    CatalogueID : 2513

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Target NOD2
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym NOD2 Antibody: Caspase recruitment domain 15, CARD15
Format NOD2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases PSORAS1, BLAU, CARD15, CD, CLR16.3, NOD2B, IBD1, ACUG, NLRC2
Description NOD2 Antibody: Apaf-1 and NOD1 are members of a new family, which are involved in the regulation of apoptosis and immune response. Each of them contains a caspase recruitment domain (CARD) and a nucleotide-binding oligomerization domain (NOD). A third member in this family was recently identified and designated NOD2. NOD2 interacts with RICK via a homophilic CARD-CARD interaction. NOD2 activates NF-κB, which is regulated by its carboxy-terminal leucine-rich repeat domain that acts as an intracellular receptor for components of bacteria. The variants of NOD2, either a frameshift or a missense, were associated with Crohn's disease that is a main type of chronic inflammatory bowel disease
Cite This Product ProSci cat# 2513 RRID:AB_713032
Company ProSci
Type Antibody
Accession Number Q9HC29
Immunogen Rabbit NOD2 polyclonal antibody was raised against a synthetic peptide corresponding to 14 amino acids at the carboxy terminus of human NOD2
Isotype IgG
Molecule Name NOD2 nucleotide-binding oligomerization domain containing 2
Clonality Polyclonal