Rabbit Anti-Human Caspase-1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human Caspase-1 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 3463

  • Contact Vendor

Target CASP1
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym Caspase-1 Antibody: ICE, IL-1beta converting enzyme
Format Liquid, Caspase-1 Antibody is supplied in PBS containing 0.02% sodium azide
Concentration 1 mg/mL
NCBI Gene Aliases P45, IL1BC, ICE
Description Caspase-1 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Caspase-1 was initially identified as an IL-1β-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts
Cite This Product ProSci cat# 3463 RRID:AB_713037
Company ProSci
Type Antibody
Accession Number NP_150634
Immunogen Caspase-1 antibody was raised against a 15 amino acid synthetic peptide from near the middle of human Caspase-1
Isotype IgG
Molecule Name CASP1 caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
Clonality Polyclonal