Rabbit Anti-Caspase-2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Caspase-2 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3447

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Target CASP2
Species Cross Reactivity Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB
Target Species Homo sapiens
Target/Molecule Synonym Caspase-2 Antibody: ICH-1, Nedd2
Format Caspase-2 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases NEDD-2, ICH-1L, NEDD2, CASP-2, ICH1, ICH-1S
Description Caspase-2 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1β and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death
Cite This Product ProSci cat# 3447 RRID:AB_735335
Company ProSci
Type Antibody
Accession Number P42575
Immunogen Caspase-2 antibody was raised against a 16 amino acid synthetic peptide from the amino-terminus of human Caspase-2
Isotype IgG
Molecule Name CASP2 caspase 2, apoptosis-related cysteine peptidase
Clonality Polyclonal