Rabbit Anti-Mouse CCR1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Mouse CCR1 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-270

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Target CCR1
Species Cross Reactivity Mus musculus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Target Species Mus musculus
Target/Molecule Synonym CCR1, CC-CKR-1, CCR-1, CD191, CKR-1, CMKBR1, CMKR1, HM145, MIP-1ALPHA-R, MIP1AR, RANTES-R, SCYAR1, c-c chemokine receptor 1, cc chemokine receptor 1, ccr1, ckr1, cmkbr1, hm145, macrophage inflammatory protein 1-alpha receptor, MIP-1 alpha, MIP-1 alpha receptor, rantes receptor
Unit 0.05 mg
Format Purification: Protein G ColumnFormulation: Weight: 50 µg Concentration: 0.5 mg/ml
Description Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6). CCR1, a Chemokine Receptor, affects stem cell proliferation and mediates systemic inflammatory responses. This receptor is stimulated by the beta chemokines RANTES, MCP-1, and MIP-1 alpha. Disruption of CCR1 enhances protection from pulmonary inflammation and reduces the development of respiratory distress syndrome in rat.Immunogen: CCR1 antibody was raised against a synthetic peptide of CCR1. (Human)Application: CCR1 antibody can be used for detection of CCR1 by WB (1 - 3 µg/ml), IHC-parafin (5 µg/ml).Buffer: CCR1 antibody is supplied in PBS, 0.05% sodium azide, 0.2% gelatin.Storage: CCR1 antibody can be stored at -20ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 49-270 RRID:AB_1945535
Company ProSci, Inc
Type Polyclonal Antibody
Isotype IgG