Rabbit Anti-ARC (CT) Polyclonal Antibody, Unconjugated

  • Rabbit Anti-ARC (CT) Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 2081

  • Contact Vendor

Target NOL3
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Homo sapiens
Target/Molecule Synonym ARC Antibody: ARC
Format ARC Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases MYP, ARC, FLJ35304, NOP, NOP30
Description ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD domain containing cell death regulators include RAIDD, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1 and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue
Cite This Product ProSci cat# 2081 RRID:AB_203134
Company ProSci
Type Antibody
Accession Number NP_003937
Immunogen ARC antibody was raised against a peptide corresponding to amino acids 191 to 208 of human origin
Isotype IgG
Molecular Weight 25 kDa
Molecule Name NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
Clonality Polyclonal