Rabbit Anti-ARC (NT) Polyclonal Antibody, Unconjugated

  • Rabbit Anti-ARC (NT) Polyclonal Antibody, Unconjugated

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    CatalogueID : 2185

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Target NOL3
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Target Species Homo sapiens
Target/Molecule Synonym ARC Antibody: ARC
Format ARC Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases MYP, ARC, FLJ35304, NOP, NOP30
Description ARC Antibody: Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD. ARC interacts with caspase-2 and -8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue
Cite This Product ProSci cat# 2185 RRID:AB_203135
Company ProSci
Type Antibody
Accession Number NP_003937
Immunogen ARC antibody was raised against a peptide corresponding to amino acids 2 to 18 of human origin. These sequences are identical to those of human nuclear protein Nop30 (2) and differ from those of the rat homolog of ARC by one amino acid (3)
Isotype IgG
Molecular Weight 25 kDa
Molecule Name NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain)
Clonality Polyclonal