Rabbit Anti-BAP31 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-BAP31 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3665

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Target BCAP31
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Homo sapiens
Target/Molecule Synonym BAP31 Antibody: BAP31, B cell receptor-associated protein 31 BCR associated protein 31
Format BAP31 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases BAP31, CDM, DXS1357E, 6C6-AG
Description BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death
Cite This Product ProSci cat# 3665 RRID:AB_735584
Company ProSci
Type Antibody
Accession Number NP_005736
Immunogen BAP31 antibody was raised against a 17 amino acid synthetic peptide from near the carboxy terminus of human BAP31
Isotype IgG
Molecule Name BCAP31 B-cell receptor-associated protein 31
Clonality Polyclonal