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| Target | BCAP31 |
| Species Cross Reactivity | Rattus norvegicus, Mus musculus, Homo sapiens |
| Host Species | Oryctolagus cuniculus |
| Target Tag/Conjugate | Unconjugated |
| Applications | EIA, WB, IHC |
| Target Species | Homo sapiens |
| Target/Molecule Synonym | BAP31 Antibody: BAP31, B cell receptor-associated protein 31 BCR associated protein 31 |
| Format | BAP31 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid |
| Concentration | 1 mg/mL |
| NCBI Gene Aliases | BAP31, CDM, DXS1357E, 6C6-AG |
| Description | BAP31 Antibody: Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family. These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18. It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria. Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death |
| Cite This Product | ProSci cat# 3665 RRID:AB_735584 |
| Company | ProSci |