Mouse Anti-BAX Monoclonal Antibody, Unconjugated, Clone 6A7

  • Mouse Anti-BAX Monoclonal Antibody, Unconjugated, Clone 6A7

    from ProSci
    CatalogueID : 49-979

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Target Bax
Species Cross Reactivity Mus musculus, Rattus norvegicus, Monkey (Species unspecified)
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IP
Clone Clone 6A7
Target/Molecule Synonym BAX, apoptosis regulator bax, apoptosis regulator bax, membrane isoform alpha, bcl2-associated x protein
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg
Description Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.Immunogen: BAX monoclonal antibody was raised against a synthetic peptide of BAX. (Human)Application: BAX monoclonal antibody can be used for detection of BAX by WB, IP, IHC-parafin (minimum working concentration: 10 µg/ml).Buffer: BAX monoclonal antibody is supplied in Phosphate-buffered solution, pH 7.2, 0.09% sodium azide at 0.5 mg/ml.
Cite This Product ProSci cat# 49-979 RRID:AB_1945300
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID Q07813