Rabbit Anti-BAX Polyclonal Antibody, Unconjugated

  • Rabbit Anti-BAX Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-193

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Target Bax
Species Cross Reactivity Homo sapiens, Mus musculus, Rattus norvegicus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IP
Target/Molecule Synonym BAX, apoptosis regulator bax, apoptosis regulator bax, membrane isoform alpha, bcl2-associated x protein
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Volume: 50 µl
Description Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability.Immunogen: BAX antibody was raised against the N Terminus of BAX. (Mouse)Application: BAX antibody can be used for detection of BAX by WB (2 µg/ml), IP, IHC-parafin (1:50).Buffer: BAX antibody is supplied in phosphate-buffered solution, pH 7.2, 0.09% sodium azide, 0.2% gelatin.Storage: BAX antibody can be stored undiluted at 4ºC. Do not freeze.
Cite This Product ProSci cat# 49-193 RRID:AB_1945299
Company ProSci, Inc
Type Polyclonal Antibody
Isotype IgG