Rabbit Anti-Human Bax Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human Bax Polyclonal Antibody, Unconjugated

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    CatalogueID : 3351

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Target Bax
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym Bax Antibody:
Format Bax Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases BCL2L4
Description Bax Antibody: Apoptosis plays a major role in normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes: those that inhibit apoptosis and those that promote cell death. Bax, a pro-apoptotic Bcl-2 family member, is a cytosolic protein that changes conformation and translocates to the mitochondria following apoptotic stimuli. It is thought to share significant functional homology with Bak, another pro-apoptotic Bcl-2 family member, as disruption of bax or bak has little effect on cell death, but mice lacking both genes display multiple developmental defects and cells lacking both show decreased apoptotic capability
Cite This Product ProSci cat# 3351 RRID:AB_2208598
Company ProSci
Type Antibody
Accession Number AAA03619
Immunogen Bax antibody was raised against a peptide corresponding to 16 amino acids near the amino-terminus of human Bax
Isotype IgG
Molecule Name BAX BCL2-associated X protein
Clonality Polyclonal