Rabbit Anti-Human NAIP Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human NAIP Polyclonal Antibody, Unconjugated

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    CatalogueID : 3315

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Target naiP
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym NAIP Antibody:
Format NAIP Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases FLJ18088, FLJ42520, FLJ58811, BIRC1, psiNAIP, NLRB1
Description NAIP Antibody: Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs however, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of its activity. Finally, although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported
Cite This Product ProSci cat# 3315 RRID:AB_713014
Company ProSci
Type Antibody
Accession Number AAC52047
Immunogen NAIP antibody was raised against a synthetic peptide corresponding to 13 amino acids at the C-terminus of human NAIP
Isotype IgG
Molecule Name NAIP NLR family, apoptosis inhibitory protein
Clonality Polyclonal