Mouse Anti-Human BLK Monoclonal Antibody, Unconjugated, Clone 9D10D1

  • Mouse Anti-Human BLK Monoclonal Antibody, Unconjugated, Clone 9D10D1

    from ProSci
    CatalogueID : 32-116

  • Contact Vendor

Target Blk
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Clone Clone 9D10D1
Target Species Homo sapiens
Target/Molecule Synonym MGC10442
Unit 0.1 ml
Format Formulation: Ascitic fluid containing 0.03% sodium azide. Purified antibody available at no extra cost.
Description BLK ( B lymphoid tyrosine kinase), with 505-amino acid protein (about 56KDa), belongs to the Src non-receptor tyrosine kinases family.Different subcellular localizations of Src-family kinases may be important for the regulation of specific cellular processes such as mitogenesis, cytoskeletal organization, and membrane trafficking.Blk is expressed exclusively by B lymphocytes and it is thought to function in a signal transductory pathway specific to this lineage. B lymphoid expression of an active Blk mutant caused proliferation of B progenitor cells and enhanced responsiveness of these cells to interleukin 7. Thus, sustained activation of Blk induces responses normally associated with the pre-BCR.GI Number: 640Immunogen: Ni-NTA purified truncated recombinant BLK expressed in E. Coli strain BL21 (DE3).Application: Western Blot:1:500 - 1:2,000 IHC(P)1:500 - 1:2,000 IHC(F)1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.Storage: BLK monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-116 RRID:AB_1945348
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG2a
Uniprot ID P16277