Rabbit Anti-CTNNB1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-CTNNB1 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 48-744

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Target Ctnnb1
Species Cross Reactivity Mus musculus, Rattus norvegicus, Bos taurus, Primate (Species unspecified), Ovis aries
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Target/Molecule Synonym CTNNB1, BETA-CATENIN, CTNNB, PRO2286, beta cadherin associated protein, beta-catenin, cadherin-associated protein beta 1, ctnnb
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg Concentration: 0.8 mg/ml
Description Beta-catenin is an adherens junction protein, which mediates cell-cell adhesion, cell-cell communication and contributes to cytoskeletal integrity. It is similar to the product of the Drosophila segment polarity gene armadillo. Like armadillo, beta-catenin is part of the E cadherin multiprotein complex that regulates pattern formation at several stages of embryogenesis. In addition beta-catenin is involved in wound healing and tumor cell metastasis. Beta-catenin is part of the Wnt signaling cascade. It interacts with Tcf and Lef to activate gene transcription and regulates cell growth. Beta-catenin accumulation has been observed in various cancers, especially in colorectal tumors and hepatoblastoma. Beta-catenin-mediated transcription is down regulated when the protein binds to the tumor suppressor protein APC.Immunogen: CTNNB1 antibody was raised against amino acids 43-62 of CTNNB1. (Human)Application: CTNNB1 antibody can be used for detection of CTNNB1 by WB, IHC-parafin (5 µg/ml).Buffer: CTNNB1 antibody is supplied in TBS, pH 7.4, 0.5% BSA, 0.02% sodium azide, 50% glycerol.Storage: CTNNB1 antibody can be stored at -70ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 48-744 RRID:AB_1945848
Company ProSci, Inc
Type Polyclonal Antibody
Isotype IgG