Mouse Anti-CXCR4 Monoclonal Antibody, Unconjugated, Clone 12G5

  • Mouse Anti-CXCR4 Monoclonal Antibody, Unconjugated, Clone 12G5

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    CatalogueID : 49-232

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Target CXCR4
Species Cross Reactivity Monkey (Species unspecified), Pan troglodytes, Baboon (Species unspecified)
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications IHC, FACS, IF
Clone Clone 12G5
Target/Molecule Synonym CXCR4, CD184, CXC-R4, CXCR-4, D2S201E, FB22, FUSIN, HM89, HSY3RR, LAP3, LCR1, LESTR, NPY3R, NPYR, NPYRL, NPYY3, NPYY3R, WHIM, c-x-c chemokine receptor 4, chemokine c-x-c motif receptor 4, cmkar4, cxc chemokine receptor 4, cxcr4, d2s201e, fusin, hm89, hsy3rr, lestr, npy3r, npyy3, npyy3r, seven-transmembrane-segment receptor, spleen
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg
Description CXCR4, a Chemokine Receptor involved in organ vascularization, neuronal cell migration, and patterning of the central nervous system during development. It binds stromal cell-derived factor 1 (SDF1, also called PBFS) and mediates migration of resting leukocytes and is unique in homing hematopoietic progenitors to bone marrow. These properties suggest that CXCR4 is involved in tumor cell migration and local tumor invasion. It is also an HIV-1 fusion co-factor that allows HIV-1 invasion in diverse human cell types. Although this receptor was initially called Neuropeptide Y3 Receptor, it does not respond to neuropeptide Y. CXCR4 has two isoforms that are produced by alternative splicing.Immunogen: HumanApplication: CXCR4 antibody can be used for detection of CXCR4 by FACS, IF, IHC-parafin (10 µg/ml), IHC-frozen.Buffer: CXCR4 monoclonal antibody is supplied in PBS, pH 7.2, 0.09% sodium azide.Storage: CXCR4 monoclonal antibody can be stored at 4ºC, avoid freezing.
Cite This Product ProSci cat# 49-232 RRID:AB_1945864
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG2a
Uniprot ID P70658