Mouse Anti-Human BCL10 Monoclonal Antibody, Unconjugated, Clone 4F8...

  • Mouse Anti-Human BCL10 Monoclonal Antibody, Unconjugated, Clone 4F8E8H8

    from ProSci
    CatalogueID : 32-115

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Target BCL10
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Clone Clone 4F8E8H8
Target Species Homo sapiens
Target/Molecule Synonym CLAP, Me10, CIPER, c-E10, CARMEN
Unit 0.1 mg
Format Purification: Antibody is purified by protein A affinity chromatography.
Description B-cell CLL/lymphoma 10, also known as CLAP, Me10, CIPER, c-E10, CARMEN. Entrez Protein NP_003912. It is a protein containing a caspase recruitment domain (CARD). It plays an important role in apoptosis and activating NF-kappaB. The research suggested that it interacted with other CARD domain containing proteins including CARD9, 10, 11 and 14, which were thought to function as upstream regulators in NF-kappaB signaling. Bcl-10 is found to form a complex with MALT1 which encoded by another gene known to be translocated in MALT lymphoma. MALT1 and Bcl-10 are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy.GI Number: 8915Immunogen: Ni-NTA purified recombinant human BCL-10 expressed in E. Coli strain BL21 (DE3).Application: IHC(P):Dilution 1:1,000 - 1:2,000 IHC(F):Dilution 1:1,000 - 1:2,000 Western blot:Dilution 1:2,000 - 1:5,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.Positive Control 1: Cat. No. 1219 - MCF7 Cell LysateStorage: BCL-10 monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-115 RRID:AB_1945307
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID Q9Z0H7