Rabbit Anti-Precerebellin Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Precerebellin Polyclonal Antibody, Unconjugated

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    CatalogueID : 3589

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Target CBLN1
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Homo sapiens
Target/Molecule Synonym Precerebellin Antibody: Cerebellin precursor, Cbln1
Format Precerebellin Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
Description Precerebellin Antibody: Precerebellin is the precursor of the brain-specific hexadecapeptide cerebellin, a protein with substantial similarity to the globular region of the B chain of complement component C1q. Cerebellin exerts neuromodulatory functions by directly stimulating norepinephrine release via the adenylate cyclase/pka- dependent signaling pathway; and indirectly enhances adrenocortical secretion in vivo, through a paracrine mechanism involving medullary catecholamine release. The active form of precerebellin is highly enriched in postsynaptic structures of cerebellar Purkinje cells in cartwheel neurons of the dorsal cochlear nucleus. Because precerebellin belongs to the C1q/tumor necrosis factor superfamily of secreted proteins and has similarity to adiponectin and CTRP3, it has been suggested that precerebellin posseses functions other than those already stated
Cite This Product ProSci cat# 3589 RRID:AB_735641
Company ProSci
Type Antibody
Accession Number P23435
Immunogen Precerebellin antibody was raised against a 15 amino acid synthetic peptide from the middle of human precerebellin
Isotype IgG
Molecule Name CBLN1 cerebellin 1 precursor
Clonality Polyclonal