Rabbit Anti-LAMP-1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-LAMP-1 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3629

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Target LAMP1
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym LAMP-1 Antibody: LAMP-1, Lysosome associated membrane protein 1
Format LAMP-1 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases LGP120, CD107a, LAMPA
Description LAMP-1 Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). A protein recently found to be involved in autophagy, LAMP-2, is a highly glycosylated protein associated with the lysosome. LAMP-1 shares much homology to LAMP-2 and is thought to have overlapping functions. Mice lacking LAMP-1 had very minor defects compared to those deficient in LAMP-2 expression. However, the loss of both proteins resulted in embryonic lethality, suggesting that each protein possesses some unique and necessary functions
Cite This Product ProSci cat# 3629 RRID:AB_735652
Company ProSci
Type Antibody
Accession Number NP_005552
Immunogen LAMP-1 antibody was raised against a 15 amino acid synthetic peptide from near the center of human LAMP-1
Isotype IgG
Molecule Name LAMP1 lysosomal-associated membrane protein 1
Clonality Polyclonal