Rabbit Anti-CX3CL1 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-CX3CL1 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 2099

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Target Cx3cl1
Species Cross Reactivity Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Target Species Homo sapiens
Target/Molecule Synonym CX3CL1 Antibody: CX3C, CX3C membrane-anchored chemokine, neurotactin, small
Format CX3CL1 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
NCBI Gene Aliases neurotactin, CXC3, C3Xkine, SCYD1, NTT, CXC3C, ABCD-3, NTN, fractalkine
Description CX3CL1 Antibody: Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-α in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1
Cite This Product ProSci cat# 2099 RRID:AB_735416
Company ProSci
Type Antibody
Accession Number AAB50014
Immunogen CX3CL1 antibody was raised against a peptide corresponding to 18 amino acids near the amino terminus of human CX3CL1
Isotype IgG
Molecule Name CX3CL1 chemokine (C-X3-C motif) ligand 1
Clonality Polyclonal