Rabbit Anti-Human GPR44 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human GPR44 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 48-122

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Target Gpr44
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications IHC
Target Species Homo sapiens
Target/Molecule Synonym GPR44, CD294, CRTH2, DL1R, chemoattractant receptor-homologous molecule expressed on th2, crth2, DP2 prostaglandin receptor, g protein-coupled receptor 44, gpr44, hCRTH2, prostaglandin D(2) (PGD(2)) receptor
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg Volume: 50 µl Concentration: 1 mg/ml
Description GPR44, also called CRTH2, is a Prostanoid Receptor that binds prostaglandin D2. PGD2 signals through CRTH2 to induce Th2, eosinophil, and basophil chemotaxis in a G-alpha(i) dependent manner. CRTH2 may play a role in mast cell-mediated immune responses such as those involved in allergic reactions. This receptor is upregulated in activated T helper-2 (Th2) cells, peripheral blood basophils, and eosinophils, but not in Th1 lineage cells. It may be a useful marker for Th2 and Tc2 cells.Immunogen: GPR44 antibody was raised against the C-terminal cytoplasmic domain of GPR44. (Human)Application: GPR44 antibody can be used for detection of GPR44 by IHC-parafin (15 µg/ml).Buffer: GPR44 antibody is supplied in PBS, 0.1% sodium azide.Storage: GPR44 antibody can be stored at -70ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 48-122 RRID:AB_1946609
Company ProSci, Inc
Type Polyclonal Antibody