Rabbit Anti-GLI2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-GLI2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 51-129

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Target GLI2
Species Cross Reactivity Mus musculus, Rattus norvegicus, Bos taurus, Pan troglodytes
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target/Molecule Synonym GLI2, gli-2, gli2
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg
Description Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is a nuclear protein thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes; Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, postaxial polydactyly types A1 and B. Multiple splice variants (4) have been reported for this protein.Immunogen: Antibody was raised against Corresponds to amino acids 46-60 of human Gli-2 (isoform a). (Human)Application: GLI2 antibody can be used for detection of GLI2 by IHC (1:500 - 1:2000), WB (1:500 - 1:2000), ELISA (1:2000 - 1:12000), IHC-parafin (5 µg/ml).Buffer: Antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.Storage: Antibody can be stored at 4ºC or -20ºC. Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 51-129 RRID:AB_1946516
Company ProSci, Inc
Type Polyclonal Antibody