Rabbit Anti-Rat GLI2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Rat GLI2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-617

  • Contact Vendor

Target GLI2
Species Cross Reactivity Rattus norvegicus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target Species Rattus norvegicus
Target/Molecule Synonym GLI2, THP, THP2, gli-2, gli2
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg Concentration: 1 mg/ml
Description Gli-2 (also known as Zinc Finger Protein Gli-2, GLI-Kruppel family member GLI-2 or Tax helper protein) belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors that bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling, and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. Gli-2 is also thought to play a role during embryogenesis. The encoded protein is associated with several phenotypes: Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, pre-axial polydactyly type IV, post-axial polydactyly types A1 and B. Expression has been reported for this mRNA in human testis, myometrium, kidney, lung, glioblastomas, and embryonal cell carcinomas. Multiple splice variants have been reported for this protein.Immunogen: GLI2 antibody was raised against amino acids from an internal region of GLI2. (Mouse)Application: GLI2 antibody can be used for detection of GLI2 by WB (1:500 - 1:2000), ELISA (1:15000 - 1:60000), IHC-parafin (5 µg/ml).Buffer: GLI2 antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.Storage: GLI2 antibody can be stored at 4ºC or -20ºC. Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 49-617 RRID:AB_1946514
Company ProSci, Inc
Type Polyclonal Antibody