Rabbit Anti-GLI3 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-GLI3 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 49-600

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Target GLI3
Species Cross Reactivity Mus musculus, Rattus norvegicus, Gallus gallus, Canis lupus familiaris, Pan troglodytes, Monkey (Species unspecified)
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Target/Molecule Synonym GLI3, ACLS, GCPS, PAP-A, PAPA, PAPA1, PAPB, PHS, PPDIV, gli-3, gli3
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg Concentration: 1 mg/ml
Description Gli-3 (also known as Zinc Finger Protein Gli-3 or GLI-Kruppel family member GLI-3) belongs to the GLI C2H2-type zinc-finger protein family and contains 5 C2H2-type zinc fingers. Gli-3 is very important for normal limb and brain development and is implicated in the transduction of Shh signal. Gli-3 is a nuclear protein expressed in a wide variety of normal adult tissues, including lung, colon, spleen, placenta, testis, and myometrium. Defects in Gli-3 are the cause of Greig cephalo-poly-syndactyly syndrome (GCPS); an autosomal dominant disorder-affecting limb and cranio-facial development. Two isoforms of human Gli-3 have been reported. One is the full-length protein at ~170-190kDa and the other is a truncated isoform at ~80kDa.Immunogen: GLI3 antibody was raised against amino acids 41-57 of GLI3. (Human)Application: GLI3 antibody can be used for detection of GLI3 by WB (1:500 - 1:2000), ELISA (1:6000 - 1:30000), IHC-parafin (1.25 µg/ml).Buffer: GLI3 antibody is supplied in 0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.1% sodium azide.Storage: GLI3 antibody can be stored at -20ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 49-600 RRID:AB_1946518
Company ProSci, Inc
Type Polyclonal Antibody