Rabbit Anti-GluR2 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-GluR2 Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 50-218

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Target GLUR2
Species Cross Reactivity Homo sapiens, Mus musculus, Rattus norvegicus, Gallus gallus, Danio rerio
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB
Unit 0.1 ml
Format Purification: Affinity purified
Description The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct Glutamate Receptor Subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990;Hollmann and Heinemann, 1994). The GluR2 subunit is thought to play a key role in forms of synaptic plasticity such as LTD (Chung et al., 2003)Immunogen: Peptide corresponding to amino acid residues from rat GluR2, conjugated to keyhole limpet hemocyanin (KLH).Application: The antibody has been directly tested for reactivity in Western blots with human tissue. It is anticipated that the antibody will also react with chicken, human, mouse, non-human primates and zebra fish based on the fact that these species have 100% homology with the amino acid sequence used as antigen.Buffer: GluR2 antibody is supplied as affinity purified polyclonal antibody, 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.Storage: GluR2 antibody can be stored at -20ºC and is stable at -20ºC for at least 1 year.
Cite This Product ProSci cat# 50-218 RRID:AB_1946528
Company ProSci, Inc
Type Polyclonal Antibody